哈佛大学刘小乐教授讲授的计算生物学和生物信息学导论 (2020 视频+资料）
生物信息學(xué)習(xí)的正確姿勢(shì)
NGS系列文章包括NGS基礎(chǔ)、高顏值在線繪圖和分析、轉(zhuǎn)錄組分析?（Nature重磅綜述|關(guān)于RNA-seq你想知道的全在這）、ChIP-seq分析?（ChIP-seq基本分析流程）、單細(xì)胞測(cè)序分析?(重磅綜述：三萬(wàn)字長(zhǎng)文讀懂單細(xì)胞RNA測(cè)序分析的最佳實(shí)踐教程)、DNA甲基化分析、重測(cè)序分析、GEO數(shù)據(jù)挖掘（典型醫(yī)學(xué)設(shè)計(jì)實(shí)驗(yàn)GEO數(shù)據(jù)分析 (step-by-step)）、批次效應(yīng)處理等內(nèi)容。
該課程由哈佛大學(xué)劉小樂教授教授，內(nèi)容涵蓋生物信息和高通量測(cè)序的很多方面，基本生信、轉(zhuǎn)錄組、表觀組、突變組、三維結(jié)構(gòu)和單細(xì)胞等領(lǐng)域，是不可多得的生信學(xué)習(xí)視頻和文字教程，推薦給各位朋友。
課程網(wǎng)站：https://liulab-dfci.github.io/teaching (正在申請(qǐng)授權(quán)，歡迎志同道合的朋友一起加入給視頻添加中文字幕)
課程目錄
2020 STAT115 Lect 1-1 ?Bioinfo History
2020 STAT115 Lect 1-2 ?Big Data Challenge
2020 STAT115 Lect 1-3 ?Bioinfo vs Comp Bio
2020 STAT115 Lect 1-4 ?Course Info
2020 STAT115 Lect 2-1 ?Three Generations of Sequencing
2020 STAT115 Lect 2-2 ?FASTQ and FASTQC
2020 STAT115 Lect 2-3 ?BLAST and Suffix Arrays
2020 STAT115 Lect 2-4 ?BWT and LF Mapping
2020 STAT115 Lect 2-5 ?Borrows-Wheeler Alignment
2020 STAT115 Lect 2-6 ?SAM and BAM files
2020 STAT115 Lect 3-1 ?RNA-seq Experimental Design
2020 STAT115 Lect 3-2 ?RNA-seq Alignment and QC
2020 STAT115 Lect 3-3 ?RNA-seq Quantification
2020 STAT115 Lect 3-4 ?RNA-seq Read Distribution
2020 STAT115 Lect 4-1 ?Differential RNA-seq
2020 STAT115 Lect 4-2 ?Multiple Hypotheses Testing and False Discovery Rate
2020 STAT115 Lect 4-3 ?Gene Ontology
2020 STAT115 Lect 5-1 ?Gene Set Enrichment Analyses
2020 STAT115 Lect 5-2 ?Consensus Clustering
2020 STAT115 Lect 5-3 ?Hierarchical Clustering
2020 STAT115 Lect 5-4 ?K-means Clustering
2020 STAT115 Lect 6-1 ?KNN and MDS
2020 STAT115 Lect 6-2 ?PCA
2020 STAT115 Lect 6-3 ?Batch Effect Removal
2020 STAT115 Lect 8-1 ?scRNA-seq
2020 STAT115 Lect 8-2 ?Processing and QC scRNA-seq
2020 STAT115 Lect 8-3 ?Differential Expression in scRNA-seq
2020 STAT115 Lect 9-1 ?scRNA-seq Batch Effect Removal
2020 STAT115 Lect 9-2 ?Gene Expression Module Summary
2020 STAT115 Lect 9-3 ?Gene Expression Analysis Scenario
2020 STAT115 Lect 10-2 ?Expectation Maximization for Motif Finding
2020 STAT115 Lect 10-3 ?Gibbs Sampling for Motif Finding
2020 STAT115 Lect 10-4 ?Motif Finding General Practices
2020 STAT115 Lect 11-1 ?ChIP-seq
2020 STAT115 Lect 11-1 ?Transcription Regulation
2020 STAT115 Lect 11-2 ?MACS and QC for ChIP-seq
2020 STAT115 Lect 11-3 ?TF Interactions from ChIP-seq
2020 STAT115 Lect 11-4 ?TF Target Genes from ChIP-seq
2020 STAT115 Lect 12-1 ?Epigenetics
2020 STAT115 Lect 12-2 ?DNA Methylation
2020 STAT115 Lect 12-3 ?DNA Methylation Function
2020 STAT115 Lect 12-4 ?Nucleosome Positioning
2020 STAT115 Lect 13-1 ?Histone Modifications
2020 STAT115 Lect 13-2 ?Histone marks on enhancers
2020 STAT115 Lect 13-3 ?Histone marks on genes
2020 STAT115 Lect 13-4 ?DNase-seq
2020 STAT115 Lect 13-5 ?ATAC-seq
2020 STAT115 Lect 15-1 ?HiC Introduction
2020 STAT115 Lect 15-2 ?Topologically Associating Domains
2020 STAT115 Lect 15-3 ?Chromatin Compartments
2020 STAT115 Lect 15-4 ?Regulatory Network
2020 STAT115 Lect 16-1 ?Intro to Single-Cell ATAC-seq
2020 STAT115 Lect 16-2 ?Preprocessing and QC scATAC-seq
2020 STAT115 Lect 16-3 ?Analysis of scATAC-seq
2020 STAT115 Lect 16-4 ?Integrating scATAC-seq with scRNA-seq
2020 STAT115 Lect 17-1 ?Module II Review
2020 STAT115 Lect 17-2 ?Module II Practice Scenarios
2020 STAT115 Lect 17-3 ?SNP and GWAS Intro
2020 STAT115 Lect 17-4 ?GWAS Artifacts and eQTL
2020 STAT115 Lect 18-1 ?Intro Functional Annotate GWAS
2020 STAT115 Lect 18-2 ?GWAS Functional Enrichment
2020 STAT115 Lect 18-3 ?Find Causal SNPs
2020 STAT115 Lect 18-4 ?Predict disease risk
2020 STAT115 Lect 19-1 ?Introduction to Cancer Genome Analysis
2020 STAT115 Lect 19-2 ?Cancer. Mutation Characterization
2020 STAT115 Lect 19-3 ?Cancer Mutation Patterns
2020 STAT115 Lect 19-4 ?Tumor Purity and Clonality
2020 STAT115 Lect 19-5 ?Interpret Tumor Mutations
2020 STAT115 Lect 19-6 ?Find Cancer Genes
2020 STAT115 Lect 19-7 ?Summary and Future
2020 STAT115 Lect 20-1 ?Tumor Subtypes
2020 STAT115 Lect 20-2 ?Survival Analysis
2020 STAT115 Lect 20-3 ?Oncogenes and Tumor Suppressor Mutations
2020 STAT115 Lect 20-3 ?scRNA-seq Clustering and Visualization
2020 STAT115 Lect 20-4 ?Cancer Epigenetics
2020 STAT115 Lect 20-5 ?Cancer Hallmarks
2020 STAT115 Lect 22-3 ?Tumor Immune Deconvolution
2020 STAT115 Lect 22-4 ?Immune Receptor Repertoires
2020 STAT115 Lect 23-1 ?Immune Signaling
2020 STAT115 Lect 23-2 ?Immunotherapy Biomarkers
2020 STAT115 Lect 23-3 ?CRISPR Screens
2020 STAT115 HaploReg
2020 STAT115 GWAS catalogue
2020 STAT115 LD Link
2020 STAT115 OpenCRAVAT Demo
視頻地址：https://www.youtube.com/watch?v=UNAUcAojgh4&list=PLeB-Dlq-v6tY3QLdQBA7rwb4a7fK9mLpv&index=3 (點(diǎn)擊閱讀原文直達(dá))。
正在申請(qǐng)授權(quán)，歡迎志同道合的朋友一起加入給視頻添加中文字幕。
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